What are the strange alphanumeric expressions in the title of this post?
Are they stock numbers?
Perhaps the key to cornering the market?
No. They’re human genes, but they are–potentially–the solution to a raging social issue: the embryonic stem cell debate.
Writing in The Weekly Standard, Ryan Anderson–an assistant editor at First Things–states:
The stem cell wars are over. Leading scientists are telling us that they can pursue the most promising stem cell research without using–much less killing–human embryos. This breakthrough enables researchers to create human embryonic stem cells directly from adult cells. In fact, the new method may actually prove superior to embryo-destructive alternatives. This is the biggest stem cell advance since James Thomson became the first scientist to isolate embryonic stem cells, less than a decade ago.
It is a new study by Thomson himself that has caused the present stir, but this time Thomson is not alone. Accounts of independent research by two separate teams of scientists were published on November 20–one in the journal Cell and one in the journal Science–documenting the production of pluri-potent human stem cells without using embryos or eggs or cloning or any morally questionable method at all.
The new technique is so promising that on November 16, Ian Wilmut announced that he would no longer seek to clone humans. Wilmut, you may remember, is the scientist who cloned Dolly the sheep. He recently sought and received a license from the British government to attempt to clone human embryos for research purposes. Now, citing the new technique, he has abandoned his plans.
Now, I’ve head prospective ways of creating pluripotent stem cells without embryos before–and I haven’t been convinced that they were what they were said to be. The ones I’ve heard before struck me as ways of creating, or potentially creating, severely deformed human embryos and harvesting their stem cells, so I’m skeptical of new miracle procedures that will get around the problem.
I’d like to learn more about the technique that Anderson writes about, but from the description he gives of it in his Weekly Standard article, it sounds as if we may have the genuine article here.
The idea is that you take adult cells and–rather than turning them into totipotent stem cells, which could conceivably be an embryo under another name, you reprogram only select genes in them–those in the article title–and you get a pluripotent-but-not-totipotent stem cell directly from an adult cell.
If that’s what’s really happening in this technique, we may–indeed–have a solution to the stem cell wars.
If so, we have a cause for rejoicing.

